A member asked:

Cea is rising 1 point per month while on irinotecan . does this mean not responding to treatment ?

3 doctors weighed in across 2 answers
Dr. Kris Gast answered

CEA and chemo: If the CEA has been used to monitor response to treatment than a rise and a steady rise would mean that cancer is producing the CEA. It might be a good time to actually go back and plot the values to make sure the rise is real. If so a repeat of scans might be in order

Answered 1/14/2015

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CEA often fluctuates: We have to give 2 months of chemo before we can assess response. CEA is not enirely reliabnle unless you have done it 3-4 times in a row, one month aprt. Then it will show us a trend for tumor being better or worse. Yet we rely much more on Imaging studies(CT scan etc) along with patient symptoms and doctor's examination. All together(these 4 items) will help us conclude if tumor is getting small

Answered 1/14/2015

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