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A member asked:

Cea rising on irinotecan since started in october . 1 point increase each month . cea 10 at present . is chemo not working ?

A doctor has provided 1 answer

Possibly not working: Irinotecan is an antineoplastic agent that interferes with the production of proteins necessary for cancer cell growth and reproduction. It is used primarily for treating cancer of the colon and rectum. While the CEA is of some value in monitoring one must be able to define if a rising marker does indicate drug failure. Here a PET/CAT scan can show if there is recurrence or progression of disease

Answered 1/9/2015

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Can a 1 point CEA rise per Month on irinotecan mean chemo not working ? Irinotecan started in oct. Oct cea-8 Dec cea-9 Jan cea-10
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