I have high rnp with joint pain, fatigue, weakness, low grade fevers. my rheumatologist says rnp means nothing?

Is that so?: The real question is, "Should we bring out the big guns and treat you for mixed connective tissue disease with a high (how high?) RNP titer and clinically not enough to make the call of MCTD?" Often fitness training, NSAIDS, even something as simple as plenty of water, and even a relationship with a local holist / complementary practitioner can be helpful while waiting for further symptoms.