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A member asked:

Since flexeril (cyclobenzaprine hcl) is closely related to amitriptyline, does that mean flexeril (cyclobenzaprine hcl) has antidepressant effects?

2 doctors weighed in across 2 answers

Not on the label: It may but by label that is not the indication. It is like a tri-cyclic antidepressant.

Answered 9/4/2020

3.4k views

Thank
Dr. Darrell Herrington answered

Specializes in Family Medicine

No: Flexeril (cyclobenzaprine hcl) and Amitriptylline are not closely related in structure or function.

Answered 7/16/2015

3.4k views

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