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A 31-year-old member asked:

How long does it take your system to flush out the effects of flexeril (cyclobenzaprine hcl)?

1 doctor answer1 doctor weighed in
Dr. Syed H. Sajid
General Adult Psychiatry; Child & Adolescent Psychiatry ( 1 yr. Fellowship), sees all types of patients for Medication Management from ages 6-99yo 30 years experience
Half life 8-37 hrs.: Half life of cyclobenzaprine ranges from 8-37 hours, with the average half life being approximately 18 hrs. It is metabolized in the liver through the cyp450 enzyme system. So, the effects of Flexeril (cyclobenzaprine hcl) may leave your system in approximately 18 hours.

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Last updated Oct 2, 2018


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