ABO incompatability: Generally, if the mother is known to be of O blood type, we also check the baby's blood type as well as check for antibodies in the baby's blood (direct Coombs test). If there is ABO incompatibility, positive coombs, high reticulocyte count and early jaundice then the baby will possibly require an exchange transfusion to prevent kernicterus
Answered 2/19/2015
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