A member asked:

My son has ms since 20. mri says overall progressive, new demyelinating, and worsened infratentorial and supratentorial...is it secondary progressive?

7 doctors weighed in across 2 answers

Multiple Sclerosis: secondary progressive refers to descriptive course of illness and refers to progressive disability without any exacerbations in a patient who had exacerbations. Can't tell from your description.

Answered 3/26/2016

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Perspective: MS in most folks can be a progressive disorder, which needs treatment with potent meds, such as Gilenya or Tysabri (natalizumab) to prevent accumulation of disability. MRI findings suggest lack of control by current treatment approaches, but such changes confirm progression and persistent problems. Since Secondary progression can occur in 50% of pts by 10 yrs, best to find the most effective interventions.

Answered 1/9/2015

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