I was diagnosis w ms periventcular & subcortial lesions, new neuro is saying mri looks like migraines not ms, is there a difference between the lesions?

Lesions: In scan may be similar, but a good history and lack of progressive symptoms help distinguish between the two.

Depends: There are many lesions that appear on imaging as non-specific and can be seen in many lesions. There are exact criteria that are present which makes MRI useful in the diagnosis, discuss with another specialist if you are concerned and have two different opinions.

Complex: Do you have confirmed diagnosis of MS, or is this a presumption based on nonspecific MRI findings? In MS, the MRI shows changes over time, and lesions are modified, often perpendicular to ventricle and ovoid in shape. Migraine lesions typically are posterior and scattered.