On 450mg wellbutrin, (bupropion) 2mg of mirapex for depression. i do not have rls/parkinsons. mirpex cause bad insomnia. sinemet might be be better option?

Probably not: if you do not have Parkinsonism Or rls. I am not sure why you would need mirapex or simemet in combo with Wellbutrin (bupropion). All 3 are dopamine agonists and could contribute to insomnia. I have used mirtazepine or paroxetine in combination with Wellbutrin (bupropion). Both are antidepressants and usually sedating, but discuss with prescribing doc. There may be some other reason you are on the mirapex