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A female asked:

Tried ssri/xanax for depression/anxiety, bad reactions. i heard wellbutrin (bupropion) works on different brain chemicals than ssri's. can wellbutrin (bupropion) help?

2 doctor answers2 doctors weighed in
Dr. John Gaffney
Psychiatry 27 years experience
Wellbutrin (bupropion): Wellbutrin does work on different neurotransmitters than SSRI's - specifically norepinephrine and dopamine. That said, you mentioned using Xanax (alprazolam) in the past - and Wellbutrin does have an "activating" effect for many people. So, it's probably not the best option for you. I'd suggest seeing a psychiatrist to talk over all of the options available (sometimes dosing is the key). Good luck!
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Judith Tellerman
Clinical Psychology 44 years experience
DEPRESSION: Antidepressants help but may not be enough because they do not teach you coping mechanisms. Psychotherapy with a Clinical Psychologist with expertise in multiple types of psychotherapy can help your medications to work better. Best to discuss medication with a Psychiatrist. If not comfortable with your Dr. see another for a second opinion & have a physical exam to rule out illness.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Jan 14, 2021


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