How long after taking tylenol (acetaminophen) cold severe do i need to wait to drink alcohol?

Alcohol : and any medications in my opinion don't mix. If you are sick enough to take cold medicine then you're too sick to drink for 24+ hours.

Avoid Tylenol (acetaminophen) Cold: Avoid "Tylenol Cold Severe", unless ordered to by a doctor. It contains phenylephrine, which doesn't treat the viruses which cause colds, & which has side effects including increased blood pressure, racing heart, risk for stroke and heart attack, dry mouth, insomnia, urinary retention - by drying your mucus membranes, it can prolong your infection.

Don't take: As a general rule: Don't take Tylenol(*T) if you are drinking, and don't drink alcohol (*A) if you are taking*T.*T is metabolized in the liver and changed into chemicals that are excreted in the urine.*A(interferes with this process and a chemical toxic to the liver builds up, which can cause liver failure.(more likely if you've consumed *A for several days in a row or take>6 ExTra Strength Caps/day