A member asked:

How long does it take the first dose of 20mg prednisone to work for inflamed throat from mono?

4 doctors weighed in across 3 answers

Steroids: Can take a good day or so for it to start working, but the swelling should subside soon. Feel better.

Answered 9/9/2015

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Not Immediately: The onset of action and relief is not immediate. Onset of action could be 8-12 hours and a severely inflamed throat could take 24 - 48 hours for significant relief of pain in mono.

Answered 12/5/2014

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Dr. David Lipkin answered

Specializes in Internal Medicine

Should not be used: According to UpToDate,Corticosteroids have NOT been shown to be helpful for routine cases of EBV infectious mono,and two studies have reported severe complications resulting from using corticosteroids in routine cases of mono. Paradoxically,corticosteroids are indicated for severe airway obstruction from mono,and appear to be helpful for overwhelming mono leading to liver failure or severe anemia

Answered 5/25/2016

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