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A 65-year-old female asked:

in my blood test results, ana came back negative. what does this mean?

2 doctor answers6 doctors weighed in
Dr. William Lages
Rheumatology 68 years experience
Nothing: An ANA test, either positive or negative, means nothing without the clinical context. It has been found negative in people with disease and positive in people with no disease. Need to ask ordering doctor.
Dr. John Chiu
Allergy and Immunology 57 years experience
Nothing: A disease is not diagnosed by any single blood test. Testing is used to confirm one's suspicion of a disease. Thus a negative ANA per se does not tell you anything. On the other hand, why was it obtained in the first place?

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How are ANA blood tests related to autoimmune disease?

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One marker: Anti-nuclear antibodies (ANA) are one marker of auto-immune disease. There are sub-types of ANA that have specificity for different diseases. The antibodies may not be the casue of disease, but a marker of the disorder.
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A member asked:

My daughter just came back from haiti..She has a 1" radius of redness with a black center? Is this a spider bite? She is having pain with it.

3 doctor answers3 doctors weighed in
Dr. Cornelia Franz
Specializes in Pediatrics
Could be : She needs to be seen and have that evaluated. Black center means a necrotic center and may need to be debrided. Make an appointment.

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Last updated Nov 5, 2019
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