Reducing oxynorm & lyrica (pregabalin) from 40 & 600mg to 100 & 10mg tapered but bad restless legs since last reduction how long will withdrawel sypmtoms last?

Depends: on the type of withdrawal! Opiate withdrawal typically 1 week AND generally up to a month on the restless leg effect so I've heard (not commonly seen since non-narcotic meds like muscle relaxers and parkinson's meds treat this). Lyrica withdrawal is 1-2 weeks OR LESS. If there is underlying restless leg like about 10-20% of the population, then...it isn't withdrawal and the symptoms stay.