Serotonin syndrome: When ppl overdose on an ssri, the clinical consequence is usually serotonin syndrome, which can manifest with a fever, sweating, mental status changes, myoclonus, etc. Depending on severity, patients can be hospitalized, given IV fluids, benzodiazepines (to reduce agitation and/or myoclonus), Cyproheptadine (blocks serotonin), and other interventions to control body temp, vitals, etc.
Answered 2/3/2017
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