A member asked:

Was just prescribed ketoprofenfor back pain will it interfear with venlafaxune 150 mg ?

3 doctors weighed in across 3 answers
Dr. George Valdez answered

Specializes in Family Medicine

No: It should be fine. A pain med called tramadol or ultram will raise flags because it has a little bit of serotonin property like venlafaxine, but overall it's fine as well in small amounts.

Answered 3/26/2013

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Bleeding: The combo may increase the risk of bleeding. The NSAID antiplatelet effects are augmented by inhibition of platelet serotonin uptake. Caution advised.

Answered 9/28/2016

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Yes. Bad Combo: The prior answer is totally wrong! the combination is dangerous because the anti platelet effect of Ketoprofen is exacerbated by the serotonin reuptake blockage caused by venlafaxine.

Answered 6/26/2014

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