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A member asked:
Could low estrogen be a cause of high morning cortisol (40)? how bad is a morning cortisol of 40?
A doctor has provided 1 answer
No: Hi. No, low estrogen does not cause high AM cortisol. Estrogen stimulates cortisol binding globulin (CBG) and thus total cortisol (free cortisol remaining normal). Low estrogen would predictably cause lower cortisol. If CBG is constitutively elevated, total serum cortisol is elevated. An AM cortisol of 40 is quite abnormal. Does your doc suspect Cushing's? Do urine cortisol and dex suppression.
Answered 11/17/2014
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