A 35-year-old member asked:
what antiviral drug prevents the attachment and penetration of hiv into t lymphocytes?
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HIV Fusion & Entry: In order for the HIV virus to enter CD4+ "Helper" Tcells, HIV glycoproteins gp120 and gp41 interact with the CD4+Tcell receptor and CCR5 and CXCR4 on the CD4+ Tcell. There are two FDA drugs that are either fusion or entry inhibitors. The reason these drugs are important is because some patients become resistant to the other classes and these can be used. AIDS.GOV link: http://tinyurl.com/h3r97tp
Answered on Jan 30, 2016
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