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Londonderry, NH
A 27-year-old female asked:

Can i take percocet and trazodone together? percocet makes me stay awake all night. even if i take it at noon i can't sleep at night.

5 doctor answers6 doctors weighed in
Dr. Donald Colantino
Internal Medicine 61 years experience
Yes: Percocet and trazadone can be taken together if these medications were prescribed for you. It is unusual that Percocet would act as a stimulant and keep you awake for hours.
Dr. Dean Giannone
Internal Medicine 25 years experience
I don't like it.: Personally, I don't like medicating the side effect of another medication. If Percocet is causing you troubles like this, perhaps you need a different analgesic.
Dr. Paul Grin
Pain Management 36 years experience
Yes, you can: but you should be closely monitored and the dosage should be carefully adjusted because percocet and trazodone both increase sedation and drowsiness.
Dr. Marino Tavarez
A Verified Doctoranswered
A US doctor answeredLearn more
Psychoactive meds: like Trazodone may potentiate (increase) effects of narcotics like oxycodone and if taken together should be done so carefully ..
Dr. Olakitan Akinjagunla
Specializes in Internal Medicine
Insomnia: Both medications may cause insomnia. It is important to get enough sleep,contact your doctor to see if the percocet can be changed or another medication added to help you sleep. Meanwhile,set a schedule for bed daily,avoid drinking caffeinated beverages,eat healthy,regular exercise only as tolerated and adequate fluid intake

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Last updated Feb 1, 2020

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