A member asked:

No symptoms. elevated bili over 6 months (range: 1.7-2.4). direct mildly elevated (0.4-0.7) everything else normal. no symptoms. possibly gilbert's?

5 doctors weighed in across 2 answers
Dr. John Fung answered

Specializes in General Surgery

Likely: Gilbert's syndrome (GS) is characterized by a reduction of a liver enzyme, UDP-glucuronosyltransferase, which changes indirect bilirubin to direct bilirubin. Normally GS is not associated with serious consequences. Mild jaundice may appear under conditions of exertion, stress, infections and fasting. The latter can be used diagnostically, with a period of fasting, the bilirubin should be higher

Answered 10/24/2014

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Follow it: Gilbert's raises indirect only, usually. If both direct and indirect are up, this may be one of the other minor metabolic problems with bilirubin. If your alk phos is okay for your age, and your transaminases are not up, you can follow it. If this started when you began taking some medication, consider trying a different Rx. If your other labs are out-of-range, you deserve a good workup.

Answered 11/26/2014

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