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A member asked:

Leg muscles very sore since i started methotrexate 7.5 weekly is this a common side effect. 5mg of folate (folic acid) on days without mtx?

A doctor has provided 1 answer
Dr. Vijay Karia answered

Specializes in Internal Medicine

Methotrexate effects: Muscle soreness is not a common side effect, but can happen. You should get further laboratory work up to check your liver, kidney and muscle enzymes. Yes, folate (folic acid) supplementation is recommended while taking methotrexate.

Dr Villaplana and another doctor agreed

Answered 4/28/2014

4.1k views

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People also searched for:

My hair is thinning I have bald patch I had a blood test done shows my MCV levels are high now being sent for b12and folate (folic acid) as fatigue sore muscles ?
I have off the chart high levels of both B12 and folate, with low ferritin. in a blood test. I was told long ago I cannot process folic Acid well. Now I take it with methotrexate. Could this folic be the cause of these results?
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I take 4 mg of folic acid per day with 10 mg Methotrexate weekly. Is this too much folic acid?

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