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A member asked:
Leg muscles very sore since i started methotrexate 7.5 weekly is this a common side effect. 5mg of folate (folic acid) on days without mtx?
A doctor has provided 1 answer
Methotrexate effects: Muscle soreness is not a common side effect, but can happen. You should get further laboratory work up to check your liver, kidney and muscle enzymes. Yes, folate (folic acid) supplementation is recommended while taking methotrexate.
Answered 4/28/2014
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