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A member asked:
Are all the medications that i'm taking as maintenance nephrotoxic? if yes, why did my doctor who is a nephrologist prescribe them?
3 doctors weighed in across 2 answers
Nephrotoxicity: none of the medications that you listed are nephrotixic. Gemfibrozil may be nephrotixic indirectly by causing rhabdomyolysis-muscle injury, which subsequently can cause renal injury
Answered 10/7/2014
3.7k views
Renal protective: Most medications are metabolized via the liver or kidney or both. Metoprolol is a beta-blocker. There is now research suggesting a nephroprotective effect from cyclosporine. http://www.ncbi.nlm.nih.gov/pubmed/21885994 Gemfibrozil has been shown to protect the kidney from cis-platinum http://www.ncbi.nlm.nih.gov/pubmed/11096145 http://www.ajol.info/index.php/aju/article/viewFile/98484/87758
Answered 10/7/2014
3.7k views
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