A 35-year-old female asked:
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is phenergan (promethazine) safe to take for nausea if on metoprolol.

1 doctor answer
Dr. Bennett Werner
44 years experience Cardiology
Good question: Phenergan (promethazine) raises metoprolol levels. You can use them together but should monitor HR and BP. You may need to lower the dose of the metoprolol.
Answered on Feb 9, 2020
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Dr. Bennett Werner
44 years experience Cardiology
Provided original answer
1/2 of 25 (which you take) is a very small dose and you're probably fine, but it's easy to monitor your HR and BP. Excess metoprolol can cause the average HR to drop <50 and/or the BP to fall < 100.
Oct 6, 2014

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