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A member asked:

Does zoloft (sertraline) reduce effect of tramadol ?

A doctor has provided 1 answer
Dr. Anthony Vita answered

Specializes in Psychiatry

No but...: ...combining tramadol with an SSRI such as sertraline (Zoloft) increases the chances of a very negative reaction called the serotonin syndrome. Generally the two medications should not be used together.

Dr Lewis agreed

Answered 9/10/2014

3.7k views

Thank

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