A member asked:

Is it possible to get serotonin syndrome from st johns wort, 5htp, or sam-e, when taken by themselves, and without any other medications?

A doctor has provided 1 answer

Serotonin syndrome: Is possible but is rare from herbals and natural products -- unless you took multiple doses per day. With stacking of these or combining with a prescribed anti depressant med or migraine med, then serotonin syndrome risks will escalate.

Answered 8/8/2015

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A member asked:

Is it possible to get serotonin syndrome from sam-e by itself?

A doctor has provided 1 answer

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