A member asked:

I have pmdd. i'm taking 30-150 mg 5htp and 450 st john's wort. is this safe can it cause seritonin syndrome? also if i become pregnant do i stop asap?

A doctor has provided 1 answer
Dr. Krishna Kumar answered

Specializes in Psychiatry

Medication effects: I understand your distress of PMDD. Taking 5HTP and ST John's wort can increase the risk of a rare but serious Serotonin Syndrome- Discuss with Psychiatrist: • Diagnosis of Depression, Anxiety or both • Decrease dose of 5HTP and ST John's wort • Benefits and side effects of SSRI, Wellbutrin, Effexor (venlafaxine) • Monitoring the effects • Therapy for stresses • See Gynecologist for PMDD

Answered 5/23/2016

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