Sam-e: Sam-e increases a brain chemical called serotonin. I saw no report of serotonin syndrome when it is taken by itself. However, if taken with medications that also increase serotonin, it will. Examples are Tramadol, Demerol , antidepressants, Robitussin Dm (guaifenesin and dextromethorphan)
Answered 3/16/2015
3.8k views
Although I wouldn't: expect it to occur,some people have developed serotonin syndrome from taking one serotonergic medication at low dose over a short period of time. It is usually with higher doses, mixes of serotonergic meds taken over a long period.
Answered 11/27/2017
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A doctor has provided 1 answer
A doctor has provided 1 answer
4 doctors weighed in across 2 answers
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