Sprained ankle, how long should you wait before driving?

Driving / sprain: Assuming it's your right ankle. It depends if you are a a cam boot or lace up brace and how severe your sprain. Usually you can drive with a sprain. It might be uncomfortable though

Depends on the Grade: of the sprain, ie, its severity. The low Grades might need 3-4 weeks while the more severe ones require 6-8 weeks to heal fully. It also depends on whether its your Right or left ankle. Talk to your treating Doc as he is in the best position to answer this question of yours. Good Luck.