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A member asked:

When is the best time of day to take a ppi like nexium (esomeprazole)? how long does it take before their effect wears off after taking one? thanks

A doctor has provided 1 answer

Dropping That Acid: In general it's advised to take at 'bedtime'because gastric acid secretion is higher between 10pm and 2am in most people.If you are taking a delayed release(DR)PPI then taking it sooner might be better.Everyone is different and so are the drugs; you'll have to find out for yourself your best dose and times.For some twice a day is better Wear-off time is longer for the DR,for the other about a day

Answered 12/15/2020

3.7k views

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