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A 22-year-old member asked:

What is pathophysiology of papillary thyroid cancer?

2 doctor answers8 doctors weighed in
Dr. Ed Friedlander
Pathology 44 years experience
Like other cancers: Like all cancers, it results from accumulated genetic mutations that cause the cells to grow inappropriately and eventually destabilize the genome. A variety of mutation groups are known. Most subtypes of papillary carcinoma of the thyroid are not especially aggressive and cures are usual.
Dr. John Yim
Dr. John Yimanswered
Surgical Oncology 29 years experience
Multiple factors.: If by pathophysiology you mean cause of papillary thyroid cancer this has not been completely defined. Undoubtedly there is a genetic component, that is what you are born with, but there is an environmental component as well. In particular, the association of radiation with papillary thyroid cancer has been found to be one of the clearest associations of an environmental factor with cancer.

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A 34-year-old member asked:

What are the steps for a papillary thyroid cancer reoccurance?

2 doctor answers4 doctors weighed in
Dr. Upendra Parvathaneni
Radiation Oncology 28 years experience
It depends: Multiple factors guide the management of a recurrent papillary thyroid ca. Patient factors - how fit and healthy tumor factors - extent of disease treatment factors - prior treatment and response and tolerance to them.
A 37-year-old member asked:

Papillary thyroid cancer follicular variant, what to do?

2 doctor answers3 doctors weighed in
Dr. Myron Arlen
Surgical Oncology 64 years experience
Remove lesion: The presence of cancer of the thyroid is best handled by thyroid resection. Depending on the size and location, a lobectomy or total thyroidectomy should be performed. Lymph nodes if present are resected. Radical neck not ut9ilized for node removal. Post oo radio iodine may be indicated and use of those meds to compensate for those anatomical structures removed.

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Last updated Sep 13, 2013

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