A member asked:

Uk clinics state that pcr rna tests for hiv should be followed by a duo test at 28 days post exposure as duo is more reliable after 28 days. opinions?

2 doctors weighed in across 2 answers

CDC guidelines: For CDC guidelines regarding testing for HIV see the site below. Nucleic acid testing for HIV is more sensitive and specific. http://www.aidsmeds.com/articles/CDC_testing_protocol_1667_25832.shtml

Answered 5/1/2017

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HIV: It is conceivable that one might test negative by PCR at a very early stage of acute HIV infection, although that is not a likely occurrence. The follow-up with a DUO test which measures p24 antigen and antibody to HIV in 28 days seems unnecessary, and repeating the PCR might be more appropriate, although far more expensive.

Answered 9/23/2014

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