A 38-year-old male asked:
Disclaimer

taking 1mg of tenex (guanfacine) every night made me somewhat hypersexual. however, taking 2mg several days ago made me impotent. can someone please explain how alpha-2 agonists cause impotence?

1 doctor answer
Dr. Carrie Cannon
A Verified Doctor answered
A US doctor answered Learn more
Alpha 1&2 receptors: Try one and one half. It seems that alpha 2 blockade is used in impotence to increase nitric oxide, but it seems you need both alpha 1 and 2 blockade to block vasoconstriction, since alpha 2 also block the release of norepinephrine and that will increase with alpha blockers. http://www.ncbi.nlm.nih.gov/pubmed/10845761
Answered on Sep 21, 2014

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Personalized answers
Free
Talk to a doctor
24/7 visits
$15 per month

Related questions:

A 38-year-old male asked:
Dr. Philip Miller
A Verified Doctor answered
A US doctor answered Learn more
BP control: Stop the hydrocodone and ask your physician about another BP medicine that will not affect your sex life. Get you male hormone levels and prostate che ... Read More
1
1 thank
A 38-year-old male asked:
Dr. Richard Zimon
59 years experience Internal Medicine
More Info please: A single dose of ANYTHING is UNLIKELY to produce impotence, or ANY of the disorders you mention. Need more information for a more specific answer1 H ... Read More
A 38-year-old male asked:
Dr. Amrit Singh
51 years experience Cardiology
Both: mostly from Tenex, (guanfacine) use other drugs which are safer, as per ur md
A 38-year-old male asked:
Dr. Alvin Lin
Dr. Alvin Lin answered
30 years experience Geriatrics
No & maybe: I'm still curious as to why you're taking Tenex (guanfacine) as you list tinnitus but not high blood pressure. Research suggests that while Tenex may ... Read More

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Personalized answers
Free
Talk to a doctor
24/7 visits
$15 per month