do people with transplanted organ need immunosuppressive drugs forever?

Question

Is it safe to stop anti rejection drugs for organ transplant after 3 years since no complications developed?

Answer 1

Yes: The chance of developing acute rejection decreases over time after an organ transplant, so often the dosage and number of immunosuppressive drugs needed can be lowered. For almost all patients, however, the need for immunosuppressive meds remains the rest of their lives following organ transplants.

Answer 2

In General, Yes: However, identical twins (same placenta) don't since they do not reject organs and tissues. In addition, there may be a few recipients with a sluggish immune system that don't appear to reject their transplanted organ. We call this tolerance, and it is a very hot area of research. The doses of is drugs usually can be decreased over time, and some recipients actually take very little.

Answer 3

Depends : It depends on the organ but everyone will have some level of pain. You will be on medication for the rest of your life to prevent rejection. You will be at a higher risk for infection and certain types of cancers. You will still have to see your doctor on a regular basis. Each organ transplanted has its own unique expected recovery.

Answer 4

Rejection: Your immune system sees any transplant as a foreign object. It treats the cells of the transplant just like bacteria cells it works to destroy them. This would cause the transplant to be destroyed or rejected. The immunosuppression runs down the volume of the immune system so it cannot kill off the transplant so easily.

Answer 5

Identical difficult: One of the functions of the immune system is recognize "self" from "non-self". Although as close a match between donor and recipient is attempted except for identical twins a "perfect" match is almost a mathematical impossibility. Therefore there are one to multiple immunologic differences that stimulate an immune response or regection.

Answer 6

Foreign proteins: Everyone has a unique genetic make up which determines the types of proteins found in our body (only identical twins have the exact same genes). Our immune systems are designed to recognize and destroy all proteins that are "foreign" (i.e. Not our own). A transplanted organ contains someone else's proteins, thus the body sees it as foreign and attacks/rejects it. Medications prevent this.

Answer 7

Well....: First, this is not a LIVE probiotic if it is a dried capsule. The consensus of benefit is only on LIVE culture. http://www.ncbi.nlm.nih.gov/pubmed/24912386 Vitamin C may cause kidney stones. It is probably helpful in maintaining grafts (in transit, NOT after they are inside someone) but hasnt been shown to do much otherwise http://www.ncbi.nlm.nih.gov/pubmed/25599738

do people with transplanted organ need immunosuppressive drugs forever?

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