A member asked:

My wife has severe ra and takes a high dose of methotrexate weekly..do we need birth control or can she even get pregnant while on the methotrexate?

5 doctors weighed in across 2 answers
Dr. Gena Kluwe answered

Specializes in Internal Medicine

Methotrexate not bc: While Methotrexate isn't *helpful* with conception, it isn't going to make your wife sterile. I would suggest good contraception.

Answered 6/28/2014

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See details: Pregnancy can occur while on methotrexate. If it does occur Methotrexate is likely to cause major abnormalities in the fetus. Use contraception.

Answered 10/4/2016

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