Double mastectomy where should i draw labs from? ankle

Depends: For what? The critical item is to avoid arm trauma, infection, lymphangitis and disabling swelling. Your physician will help minimize your blood draws. If you have great easily approachable ankle or leg veins that is a possibility. Note that trauma to the saphenous system can make those veins unusable for bypasses. With excellent technique and good arm veins, drawing from arm can be considered.

Your arm: Draw blood from your arm on the side that no lymph node surgery was performed. If there were bilateral lymph node surgery, I would still rather draw blood from your arm. If there is lymphedema or significant swelling then lower extremity can be used. Preferably a femoral vein aspiration by someone experienced to do that rather than ankle to have lesser risk of phlebitis.