A member asked:

Please advise how rare is a familial mutation on cyp19a1 gene in terms of excessive expression of estrogen synthase in male population. thank you.

A doctor has provided 1 answer
Dr. Carlos Barrera answered

Specializes in Endocrinology

Cyp19A1: Extremely rare. Apparently 24 case reports in the literature of males with this problem. It is autosomal recessive, which means both of you parents would have to be carriers for you to have a 50% chance of having this problem.

Answered 8/30/2014

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