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A member asked:
My father in law has been diagnosed with dsp gene mutation (woolly hair). my husband is being tested. if my husband is clear do my children still have to be tested? can the gene skip a generation? thank you?
A doctor has provided 1 answer
A review of available information cites the DSP gene defect as being expressed by autosomal recessive inheritance. This means one defective gene must be inherited from both parents. If we assume you have inherited one gene, your husband must carry one for your kids to inherit the defect.
Answered 7/6/2021
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