A member asked:

Any methotrexate side effects?

A doctor has provided 1 answer
Dr. Thomas Namey answered

Specializes in Rheumatology

Plenty : XX oral dos: Methotrexate is a surprisingly effective drug for many forms of arthritis and the consensus 1st choice for RA by the acr and eular (european). The oral dosage is more problematic because of variable absorption and first-pass effect through liver. It is completely absorbed with sucutaneous injection and doesn't bolus liver. Hair loss can be a problem. Everyone should take 2mg of folic acid.

Answered 12/21/2016

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