A member asked:

For dose 6 of methotrexate for ctd, my dose is increased. i take on tues but concern w/ side effects & work.okay to take 4 days early (sat from now on)? my rhemd said okay 2switch to a day that works.

4 doctors weighed in across 2 answers
Dr. Robert Lowe answered

Specializes in Pediatric Rheumatology

Calll your rheum doc: Depending on your dose, how well you've tolerated it (side effects, liver enzyme elevation, if any), it's probably not advisable to take your next dose 4 days early.For my patients, i recommend not taking 2 doses closer than 5 days apart to adjust the day they take their Methotrexate or if they take it 1 or 2 days late for some reason (sick, forgot).Call your rheum doc to get best guidance for you.

Answered 3/27/2015

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Yes: It's okay to switch to Saturday. Remember not to do your blood tests on the same day as you take your methotrexate (MTX). The blood test monitoring for MTX is sometimes abnormal (but not significant) on the day or the day after taking MTX.

Answered 3/12/2018

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