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A member asked:
How to lower shbg? it is hugely over reference range. am 62yr fit, healthy. estradiol, thyroid, liver great, but free testos dropping as shgb climbs
A doctor has provided 1 answer
Check w/your: doctor and repeat lab. SHBG levels increase with estrogenic states (oral contraceptives), pregnancy, hyperthyroidism, cirrhosis, anorexia nervosa, and certain drugs. The increase in SHBG shouldn't lower your free testosterone unless you are also developing testosterone deficiency. You need further work-up.
Answered 1/31/2015
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