A 39-year-old member asked:
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how are you supposed to work out the progesterone and estradiol ratio to know if your thyroid results are normal?

2 doctor answers
Dr. Robert Lang
51 years experience Endocrinology
You do not have to: While the ratio of Progesterone and Estradiol will affect how you feel, it will not substantially affect the thyroid tests. However, oral Estradiol will increase thyroxine binding globulin and thus increase the T4 level but the free T4 will remain stable. Because it will also increase the risk of blood clots it is advisable to use a transdermal, buccal or sublingual form of estrogen replacement.
Answered on Jan 23, 2019
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6 thanks
Dr. William Nall
14 years experience Sports Medicine
Don't worry about it: I would not worry about it. Basically if you feel good and your thyroid results are normal, then it's fine. If you do not feel good and your thyroid tests are "normal" well that's up for debate.
Answered on Sep 16, 2013

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