A member asked:

Codeine allergy need to know. i had itching from morphine but ok so far with tylenol (acetaminophen) 3?

A doctor has provided 1 answer

Itching w/ narcotics: Itching is a frequent side effect of narcotic medications and is more likely at higher doses. It is not an allergic mechanism. Narcotics bind to the opioid receptor on mast cells causing them to release histamine, and the result is itching and possibly hives.

Answered 7/11/2016

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