A member asked:

Immunifixation identifies m spike as igg kappa polyclonal gamma globulin to consist mainly of igg kappa n lamda with fair amounts of iga means what?

A doctor has provided 1 answer
Dr. Mohammed Karim answered

Specializes in Internal Medicine

?? Chronic Infection: M spike of polyclonal IgG (kappa & lambda) globulin mostly suggest chronic infectious or inflammatory process & rarely hematologic malignancies. You need a complete work up for ch. liver disease, hepatitis B/C, ch.bacterial, viral & fungal infection, HIV, autoimmune diseases & if negative then evaluate for hematological disorder. CHECK FOR Ch. INFECTION & HEPATITIS. Update me with your result.

Answered 1/9/2019

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