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A member asked:
Immunifixation identifies m spike as igg kappa polyclonal gamma globulin to consist mainly of igg kappa n lamda with fair amounts of iga means what?
A doctor has provided 1 answer
?? Chronic Infection: M spike of polyclonal IgG (kappa & lambda) globulin mostly suggest chronic infectious or inflammatory process & rarely hematologic malignancies. You need a complete work up for ch. liver disease, hepatitis B/C, ch.bacterial, viral & fungal infection, HIV, autoimmune diseases & if negative then evaluate for hematological disorder. CHECK FOR Ch. INFECTION & HEPATITIS. Update me with your result.
Answered 1/9/2019
3.8k views
Related Questions
A member asked:
Immunofixation, Serum FAH = Monoclonal IgG kappa immunoglobulin. Beta FAH = 10.5% Abnormal band, immunofixation to follow. I'm IgA deficient too. ??
A doctor has provided 1 answer
A member asked:
Kappa/lambda FLC ratio high (2.75) w/ normal K(10.21mg/dl) & low L(3.68mg/dl). Hem-onc unsure if ratio implies K monoclonality since serum/urine IFE ok & neither chain is elevated. Could monoclonal K be suppressing L? IgA a bit high IgG &IgM a bitlow
5 doctors weighed in across 2 answers
A member asked:
Is elevated kappa/lambda ratio on serum FLC test inherently monoclonal, even if neither kappa or lambda is elevated? Ratio high b/c lambda is low, not because of high kappa. SPEP/UPEP & IFE normal. High IgA, low IgG. Clean marrow biopsy. Polyclonal?
2 doctors weighed in across 2 answers
A member asked:
What does a elevated igg and gamma globulin mean? Years ago I had an elevated epv igg also.
A doctor has provided 1 answer
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