A 21-year-old male asked:
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been prescribed cefalexin and amoxicilin for my sinusitis and ear infection. do these work well together? it doesn't seem like a usual prescription.

3 doctor answers
Dr. Ellen Altenburg
30 years experience Pediatrics
Somewhat: Usually both aren't prescribed at the same time, but your physician may have a good reason for doing it that I'm not aware of.
Answered on Aug 3, 2014
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2 comments
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Dr. Louis Cooper
47 years experience Pediatrics
I agree with D. Altenburg's last comment Feel better!
Aug 3, 2014
Dr. Ellen Altenburg
30 years experience Pediatrics
Provided original answer
Agree with other docs. Amoxicillin, Augmentin or a newer generation cephalosporin are the better choices.
Aug 3, 2014
Dr. Sunnie Skiles
33 years experience Pediatrics
Combination antibiot: This is an interesting combination of antibiotics for a sinus infection and ear infection. They do work ok together, though cefalexin is better for skin infections. Amoxicillin is the first choice for ear infections. I would treat a sinus infection with Augmentin, (amoxicillin and clavulanate) which is a combination of Amoxicillin and Clavulanic acid. This combination covers resistant staph and has good sinus penetration,
Answered on Aug 3, 2014
Dr. David Masiello
17 years experience Hematology and Oncology
No: These are a cephalosporin and a penicllin. It is debateable that antibiotics really offer any benefi tin the treatment of acute sinusitis, however; the perfered agent is amoxicllin or amoxicillin with calvulinate. The additon of gram positive coverage with keflex really dos enot add any value in the treatment of sinusitis.
Answered on Sep 28, 2016

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