A member asked:

Chronic elevated alkaline phosphatase. ggt normal, other blood test negative. liver ultrasound clear. my doctors said it is a mystery of elevated ap.

2 doctors weighed in across 2 answers

Bones: Alkaline phosphates come from bone liver. If liver is fine, they should check alkaline phosphate -fractionated to rule out bone component.

Answered 2/4/2015

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Not necessarily live: Alk. Phos. can be elevated in liver disease, but the enzyme is found in other organs, including bone, biliary tract ( gall bladder), intestine and, interesting, the placenta! Certain medications can also cause an elevation.At the very least, a gallbladder ultrasound, a measurement of parathyroid hormone,calcium & phosphate levels and a review of your meds should be done.

Answered 2/4/2015

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