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Rochester, Pennsylvania
A 35-year-old female asked:

Does evening primrose oil increase estrogen? i think i'm estrogen dominant, i have pcos and wanted to try using epo. should i try it?

2 doctor answers7 doctors weighed in
Dr. Sebastian Harris
General Practice 9 years experience
Not recommended: EPO has been studied in a severe estrogen diminished state such as postmenopause. Available data suggest that it is no more effective than placebo. In the only randomized trial to address this issue 56 symptomatic postmenopausal women were randomly assigned to EPO versus placebo for six months. There was no significant difference in symptoms. And increasing estrogen can exacerbate certain cancers
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Dr. Randy Baker
Dr. Randy Baker commented
Holistic Medicine 41 years experience
While I appreciate your citing the literature, the fact that EPO does not help postmenopausal women has no bearing on whether it helps PCOS. The mechanisms via which EPO may help PCOS are related to its effects on prostaglandins and cervical mucous. Research is needed but it is plausible that it might help. See http://natural-fertility-info.com/fertility-evening-primrose-oil.html
Jul 30, 2014
Dr. Randy Baker
Holistic Medicine 41 years experience
Does not raise E but: EPO does not raise estrogen but may help PCOS by increasing Prostaglandin E and may improve fertility by increasing cervical mucous. It should be balanced with Omega 3 Fatty Acids. There is no good research proving it helps, but none showing it doesn't. It's safe to try. See http://natural-fertility-info.com/pcos-fertility-diet & click on the Evening Primrose OIl link & see http://bit.ly/1kmWQDY
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Jun 17, 2018

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