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A 31-year-old member asked:

imipramine (tofranil) and desipramine (norpramin), what are these?

1 doctor answer2 doctors weighed in
Dr. Martin Fried
General Practice 36 years experience
Antidepressants: Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. These medications can help prevent suicidal thoughts/attempts and provide other important benefits. However, studies have shown that a small number of people (especially people younger than 25) who take antidepressants for any condition may experience worsening depression

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A 42-year-old member asked:

Is desipramine a better antidepressant than nardil (phenelzine) for motivation?

1 doctor answer4 doctors weighed in
Dr. Mark Shukhman
Addiction Medicine 31 years experience
Depends: Desipramine is an old medication from the tca group. It is relatively norepinergic, that can possibly increase motivation. Nardil (phenelzine) belongs to the group of maoi, which are supposed to increase all three neurotransmitters, promote alertness etc., which also can improve motivation. I normally let my patients to try both and choose. (nb! cannot be taken in the same time!).
A 47-year-old member asked:

Is giving half of a desipramine hci 25mg. Pill safe to give to a 6 yr.Old for bedwetting ?

1 doctor answer4 doctors weighed in
Dr. George Klauber
Specializes in Pediatric Urology
Yes: 25 mg would also not be too much providing child does not experience side effects such as nightmares, cofusion or excessive dryness of mouth, headaches, costipation etc.. Have you tried, and is your child mature enough to use a bedwetting alarm? This is the most effective curative treatment for bedwetting and effective in up to 70% of kids if used correctly.
A 43-year-old member asked:

Is it bad if you mix aspirin and imipramine?

1 doctor answer2 doctors weighed in
Dr. Darshan Mahajan
Specializes in Neurology
No: Low dose Aspirin should be ok.
A 31-year-old member asked:

Are nightmares a regular side effect when taking tofranil (imipramine)?

2 doctor answers6 doctors weighed in
Dr. Robert Woods
Psychiatry 30 years experience
May Occur: Tofranil (generic imipramine) is a tricyclic antidepressants. While nightmares are reported by some patients taking tofranil, i would not consider this a regular side effect. Many antidepressants can cause an enhanced dream experience. This is a subjective experience and may be interpreted quite differently from one patient to the next. Contact your md if this is a problem. There are alternatives.
A 45-year-old member asked:

How effective is imipramine for treating premature ejaculation?

1 doctor answer1 doctor weighed in
Dr. Ed Friedlander
Pathology 44 years experience
Better options exist: A condom or a dab of a topical anesthetic on your glans may do the trick. Your physician can offer a very low dose of a selective serotonin reuptake inhibitor. Or you and your partner(s) can learn and practice the squeeze technique -- this is fun, will let you reprogram your nervous system to make you a superlatively excellent lover, and is your best long-term solution. Best wishes.

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Last updated May 18, 2015

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