Get Virtual Care
For Businesses
About Us
A member asked:
Which tcas is more potent for sciatica pain relief, amitriptyline(or nortriptyline), imipramine(or desipramine)?
4 doctors weighed in across 2 answers
TCA: Tca are classic for neuropathic pain - sciatica for example. Any of the ones u mentioned may be quite eefective - and cheap. They are not without side effects - dry mouth, constipation, sedation. Any of the ones u mentioned can be effective. I personally like amytryptilline - 10mg at night - as mentioned all will work. Additionally other meds such as lyrica, (pregabalin) neurontin, Cymbalta are options.
Answered 8/7/2016
4.2k views
Hard to say: generally though nortriptyline seems to have less side effects than the others.
Answered 2/12/2015
3.9k views
Related Questions
A member asked:
In your option which migraine preventatives do you feel most effective. I've tried amitriptyline and nortriptyline but hallucinations were bad at nigt?
4 doctors weighed in across 2 answers
A member asked:
What is the difference between amitriptyline and nortriptyline? Is one more potent for certain things. Read that nortrip helps tinnitus for instance
A doctor has provided 1 answer
A member asked:
If you are not getting the desired response on a low dose of Nortriptyline 20mg, could you switch to Amitriptyline as a straight swap?
A doctor has provided 1 answer
People also searched for:
Why is desipramine a next recommendation instead of imipramine for functional dyspepsia when amitriptyline is too sedating and stops working and nortriptyline makes heart race?
For functional dyspepsia (lower abdominal burning/nausea/loss of appetite), if amitriptyline is too sedating/tired making at low dose of 20mg but works well and nortriptyline made my heart race, should I talk to my doc about desipramine or imipramine?
For functional dyspepsia (lower abdominal burning/nausea/loss of appetite), if amitriptyline is too sedating at low dose 20mg but works well and nortriptyline made my heart race, what tryclic should I talk to my doctor about? Desipramine or imipramin?
Amitriptyline for lower abdominal burning makes me really tired 24/7 and stops working with each increase I am at 20mg now. What medications should I ask my doc about? Imipramine?? I am not compatible with Nortriptyline. PLS ONLY COMMENT SUGGESTIONS?
Is imipramine less sedating than amitriptyline? I cannot tolerate nortriptyline it makes my heart race and amitriptyline makes me tired and stips working with each increase even though it works well for IBS/lower abdominal burning?
Didn't find what you're looking for?
90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.
Ask your questionMore of what we treat
Download HealthTap
Video visit and message your doctor
