A member asked:

Why is it dangerous to take antihistamines with addarall?

4 doctors weighed in across 2 answers

Decongestant: It is not necessarily dangers to take a simple antihistamine with Adderall (dextroamphetamine and racemic amphetamine). However, if you take an antihistamine/decongestant combination (Zyrtec-D, Allegra-D, Claritin-D) the pseudoephedrine can have a stimulant effect which would be on top of the Adderall (dextroamphetamine and racemic amphetamine) effect. I would be most worried about an increase in blood pressure and the problems that could be caused by that.

Answered 7/10/2014

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Interaction: the potential sedating effect of an antihistamine will counteract the stimulant efect of Adderall (dextroamphetamine and racemic amphetamine). Speak to your doctor about an alternative combination.

Answered 4/3/2015

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