A 34-year-old member asked:
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do benadryl (diphenhydramine) and adderall interact with each other?

2 doctor answers
Dr. Michael P Vaughn
33 years experience Allergy and Immunology
Drug interactions.: Benadryl (diphenhydramine) can be sedating (typically) or stimulating (unusual) . When a reaction occurs opposite to what is typically experienced, it is called a paradoxical reaction. A pharmacist can run a drug interaction screen for you and this is why it is wise to get all of your medications from a single source. Decongestants are stimulants and often used in combination with Benadryl (diphenhydramine) and could be a bad mix.
Answered on Mar 19, 2019
Dr. Kevin Passer
34 years experience Child Psychiatry
Not directly: No, they really do different things and have different mechanisms of actions. Each can make one's mouth very dry, so the combination can make one's mouth even dryer. Other antihistamines like Allegra (fexofenadine) (fexofenidine), cause less dry mouth.
Answered on Apr 25, 2019

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A 39-year-old member asked:
Dr. Mitchell Cohen
36 years experience Psychiatry
No big risks: Adderall, a stimulant, and benadryl, (diphenhydramine) an antihistamine, have somewhat opposite effects. Adderall increases alerting brain chemicals l ... Read More
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A member asked:
Dr. Felecia Sumner
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Yes: There are no known interactions with these medicines combined.
A 47-year-old member asked:
Dr. Surendra Varma
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Yes: It should not be unsafe to take antihistamines with adderall (dextroamphetamine and racemic amphetamine).
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A 25-year-old female asked:
Dr. Eric Weisman
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12.5 mg ?: Probably can do that without much of a problem. If you google 'anticholinergic side effects' you'll know what to look for. How late did you take the a ... Read More
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